If you are prompted to install Java / JRE / (oaj2se.exe) do so.
Most of the following I found on Oracle Support site under:
Recommended Browsers for Oracle E-Business Suite Release 12 (Doc ID 389422.1)
1) In internet explorer 11 , navigate to Tools –> Compatibility View Settings . Then add your domain name in the URL (ex: oel-79.localdomain ) using Add this website option.
2) Navigate to Tools –> Internet options –> Security . Select internet and click on Custom level. Scroll down almost to the end of the options and change the option Enable XSS filter to Disable.
3) Add EBS URL as Intranet Site in Internet Options may avoid Java security related issues.